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What happens if you take ibuprofen and prednisone together?

Taking ibuprofen and prednisone together is not recommended due to the increased risk of side effects. Ibuprofen is a non-steroidal anti-inflammatory (NSAID) and prednisone is a corticosteroid. Both drugs work in different ways to reduce inflammation and swelling, however they both act on the same enzymes in the body.

Taking these two medications together can increase the risk of side effects, such as an increased risk of bleeding and stomach ulcers due to the combined effects on the same enzymes. Additionally, taking ibuprofen with prednisone may reduce the effectiveness of prednisone, resulting in reduced efficacy for the treatment of conditions such as asthma, rheumatoid arthritis, and other inflammatory conditions.

Therefore, it is important to follow your doctor’s instructions if you are prescribed both medication and not to take ibuprofen and prednisone together.