Whether or not you can plug a tire twice depends on the severity of the puncture and the type of tire. If the puncture is shallow, you may be able to plug it twice; however, the tire will be more prone to taking further damage in the future.
It is important to invest in a quality tire plug kit, as well as make sure that the tire is properly balanced and inflated after being plugged twice. If the puncture is more severe, it is not recommended that you plug the tire twice.
In this case, it is better to invest in a new tire, as the structural integrity may have been compromised in the initial puncture.