No, Voltaren Gel (diclofenac sodium topical gel) typically does not absorb into the bloodstream. However, depending on how much and where the gel is applied, absorbed amounts can vary. It is possible that with large applications of Voltaren Gel, some of it may be absorbed into the bloodstream; however, there has not been any significant research to support this.
When applied to the skin, Voltaren Gel’s active ingredient, diclofenac sodium, works to block prostaglandin synthesis, which is a common cause of inflammation and pain. This only happens at the area of application, and does not enter into the bloodstream.
Clinical studies have found that when Voltaren Gel is applied to the affected area, up to 1g in a 60-minute period, there are no very small amounts of diclofenac sodium that enter into the bloodstream—usually 0.07% or less.
Overall, Voltaren Gel is unlikely to absorb into the bloodstream, regardless of amount and frequency of application. However, because it is possible that higher concentrations or larger applications can result in some of the drug entering into the bloodstream, it is recommended that you consult with your healthcare provider before beginning to use the gel.
What is the absorption rate of Voltaren Gel?
The absorption rate of Voltaren Gel is approximately 1.5%. It is important to note that this rate is highly dependent on many factors, such as the affected area being treated, the method of administration, and the patient’s individual medical history.
When treating acute joint pain, it can take up to four weeks for the medication to take full effect. When treating chronic pain, the therapeutic effects of Voltaren Gel can become apparent within days, but its full effects take several weeks to come about.
It is important for patients to consult a healthcare provider before beginning any form of treatment with Voltaren Gel to ensure that the absorption rate is tailored to their individual needs.
How deep does Voltaren gel penetrate?
Voltaren gel has been studied and found to penetrate to a depth of about 3-4mm. This means that the medication is mainly absorbed through the skin and into the affected area where it can provide relief from inflammation and pain.
Studies indicate that voltaren gel is effective in relieving low to moderate pain associated with osteoarthritis of the knee and other joints. However, it should be noted that the deep penetration of Voltaren gel is necessary to obtain sufficient relief, and that it may take a few days of use before reaching the full level of relief.
How long does diclofenac gel take to absorb?
Diclofenac gel is absorbed quickly into the skin and is effective within 1 hour. Typically, it takes approximately 30 minutes to 2 hours for most of the active medications to penetrate the skin and enter the bloodstream and reach full therapeutic effect.
However, the total time for absorption can vary based on the amount of cream or gel being used, the location of application, and the individual’s skin type and metabolism. Additionally, some research suggests that the absorption of diclofenac gel is faster than other topical medications and can reach therapeutic concentrations in as little as 15 minutes.
To ensure that the medication is absorbed quickly and effectively, it is important to spread the gel or cream as evenly as possible on the skin and avoid covering the patient with thick dressings, which may impede the absorption process.
What are the dangers of using Voltaren gel?
Using Voltaren gel may pose a few dangers and risks, especially if you are not using the correct dose or following the directions listed on the product label.
The U.S. Food and Drug Administration (FDA) warns that prolonged use of topical diclofenac (Voltaren gel) can lead to an increased risk of serious heart problems, including stroke and heart attack. Additionally, there is a risk of serious skin reactions including Stevens-Johnson Syndrome and toxic epidermal necrolysis.
Anyone who notices signs of a severe skin reaction, like an itchy rash, blisters, or skin peeling should stop using Voltaren gel and speak to their healthcare provider right away.
Also, Voltaren gel is not indicated for use in people under 18 years of age or those with pre-existing conditions such as asthma, diabetes, chronic kidney disease, heart problems, or bleeding disorders.
Women who are pregnant or breastfeeding and individuals who are taking other medications should also be aware of the risks and speak to their healthcare provider before using Voltaren gel.
Finally, Voltaren gel is not recommended for use around the eyes, mouth, or vagina. If you do get the gel in these areas, wash the area with soap and water immediately.
Overall, it is important to read the directions on the product label before using Voltaren gel and to consult a healthcare provider if you are unsure about the safety of the product for you.
Is diclofenac gel absorbed?
Yes, diclofenac gel is absorbed into the skin. When applied topically, it is absorbed through the skin and is converted to its active metabolite, primarily the monohydroxyacid form. This form of the drug is then transported throughout the body via the circulatory system and is metabolized in the liver and excreted in the urine and feces.
Diclofenac gel is used to relieve pain and reduce swelling in certain conditions such as arthritis, bursitis, and tendinitis. It should not be applied to wounds or open skin lesions as it can be absorbed into the body.
Do you rub in diclofenac gel?
Yes, you should rub diclofenac gel into the affected area on your skin. It is important to follow the directions on the product label as you apply the gel so you can be sure you are using it correctly.
Apply a thin layer of the gel to the affected area, no more than four times per day. Gently massage the gel into the skin until it is completely absorbed. Do not apply diclofenac gel to open wounds, infected, or irritated skin and avoid contact with the eyes, nose, and mouth.
Do not apply it to any area of skin that is red, swollen, or painful. Wash your hands after applying the medication. If you develop any unusual or severe skin reactions or side effects, seek medical attention immediately.
